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Research
In my current role, I am developing deep learning methods to monitor fetal and infant brain development. I am particularly interested in the early detection of cerebral palsy from neuroimaging. During my DPhil, I developed a fully automated pipeline to characterise the healthy cortical development. I am now looking at at-risk pregnancies to see how their development varies.
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Selected Publications
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Normative growth trajectories of fetal brain regions validated by satisfactory maturation of neurodevelopmental domains at 2 years of age
Madeleine K Wyburd ... Intergrowth Consortium, Ana IL Namburete
Nature Communications, 2026
Paper / Code
Normative growth trajectories of 28 fetal brain phenotypes derived from 4205 3D ultrasound scans collected across 7 international sites. The low variance between sites reinforces the principle that the brain develops similarly when environmental constraints are minimal.
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Deep learning in fetal, infant, and toddler neuroimaging research
Madeleine K Wyburd , Jenna Chin... Lilla Zollei and Catalina Camacho
Developmental Cognitive Neuroscience, 2025
Paper
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Cross-Modality Comparison of Fetal Brain Phenotypes: Insights From Short-Interval Second-Trimester MRI and Ultrasound Imaging
Madeleine K Wyburd , Nicola Dinsdale,... Ana IL Namburete
Human Brain Mapping, 2025
Paper / Code
Comparing ultrasound and MRI fetal brain features from same day scanning.
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Anatomically Plausible Segmentations: Explicitly Preserving Topology Through Prior Deformations.”s
Madeleine K Wyburd , Nicola Dinsdale, Ana IL Namburete, Mark Jenkinson
Medical Image Analysis, 2024
Project Page / Paper / Code
Extension from the 2021 MICCAI paper.
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Normative spatiotemporal fetal brain maturation with satisfactory development at 2 years
Ana IL Namburete, Madeleine K Wyburd ... Intergrowth Consortium
Nature, 2023
Paper
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TEDS-Net: Enforcing Diffeomorphisms in Spatial Transformers to Guarantee Topology Preservation in Segmentations
Madeleine K Wyburd , Nicola Dinsdale, Ana IL Namburete, Mark Jenkinson
MICCAI, 2021 [Early Acceptance]- Conference Proceedings + Presentation
Project Page / Paper / Code
Novel segmentation method guaranteeing accurate topology.
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Automated grading of fetal cortical development using deep-learning algorithms: A preliminary 3D ultrasound study in healthy fetuses
Madeleine K Wyburd , Linde Hesse,Moska Aliasi, Felipe Moser, Monique C. Haak, Aris Papageorghiou, the INTEGROWTH-21st Consortium, Ana IL Namburete
ISUOG, 2021 - Oral Presentation
More Information Coming Soon
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Deep learning-based assessment of second trimester cortical plate development in 3D ultrasound
Madeleine K Wyburd , Aris Papageorghiou,Mark Jenkinson Ana IL Namburete
ISUOG, 2021 - Oral Presentation
More Information Coming Soon
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Using Deep Learning to Segment the Developing Cortical Plate from 3D Fetal Ultrasound.
Madeleine K Wyburd , Mark Jenkinson Ana IL Namburete
RSNA, 2020 - Poster Presentation
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Cortical Plate Segmentation using CNNs in 3D Fetal Ultrasound
Madeleine K Wyburd, Ana IL Namburete, Mark Jenkinson
MIUA, 2020 - Conference Proceedings + Presentation
Paper / Presentation
Initial cortical plate segmentation methods
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